Expert Exchange

Erica Ollmann Saphire: How the Study of HIV and Other Viruses Informed the Rapid Development of Vaccines and Therapeutic Antibodies Against COVID-19

In this interview, Dr. Erica Ollmann Saphire discusses how structural biology informs antibody drug development against COVID-19, in a sneak preview of her Keynote Address at the Keystone Symposia on “Antibodies as Drugs,” which takes place April 27-30, 2022.

>> In this second part, Dr. Ollmann Saphire shares how her work on hemorrhagic fevers prepared her, and the world, for a rapid response to COVID-19.

>>Read the Transcript.

*Video produced as a collaboration between Pathogens and Immunity and Keystone Symposia. 

KSQA with Dr. Galit Alter on Viral Immunity and Respiratory Viruses

In this interview, Dr. Alter discusses research she will be presenting at the upcoming joint Keystone Symposia on Viral Immunity: Basic Mechanisms and Therapeutic Applications and Respiratory Viruses: New Frontiers. She shares how vaccines can be formulated to shape immune responses and antibody functions, in the context of RSV, COVID and other respiratory pathogens.

>> In this second part of her interview, Dr. Alter offers career advice.

*Video produced as a collaboration between Pathogens and Immunity and Keystone Symposia. 

PAI Senior Editors Neil Greenspan, MD, PhD, and Michael Lederman, MD, Talk With David Baltimore, PhD

David Baltimore, PhD, reflects on his contributions to biomedical science, which have had a major influence on the fields of molecular biology, virology, cancer, and immunology.

>>20-Minute Video plus Transcript.





PAI Senior Editors Robert Bonomo, MD, and Michael Lederman, MD, Talk With Arturo Casadevall, MD, PhD

Dr. Arturo Casadevall shares insight into his childhood, what motivated him to go into biomedical research, the impact of the AIDS epidemic, and the lessons learned that he imparts to younger scientists.

>>20 Minute Video plus Transcript.





Peter Doherty, Nobel Laureate: Questions and Reflections Concerning MHC Restriction and other Fruits of a Life of Biomedical Erudition

Peter Doherty, PhD, talked with PAI Senior Editor Neil Greenspan, MD, PhD, about the landmark article he and Rolf Zinkernagel published in Nature that described the ability of lymphocytic choriomeningitis virus (LCMV)-specific cytotoxic T cells to lyse LCMV-infected, 51Cr-labeled target cells if the target cells shared class I major histocompatibility complex (MHC) molecules with these T cells.

>>Q&A Article.




Current Issue Articles


Use of a MAIT Activating Ligand, 5-OP-RU, as a Mucosal Adjuvant in a Murine Model of Vibrio cholerae O1 Vaccination
Published: August 24, 2022 | 10.20411/pai.v7i1.525

An ACE2-IgG4 Fc Fusion Protein Demonstrates Strong Binding to All Tested SARS-CoV-2 Variants and Reduced Lung Inflammation in Animal Models of SARS-CoV-2 and Influenza
Published: August 23, 2022 | 10.20411/pai.v7i1.491

Effect of Oral Nirmatrelvir on Long COVID Symptoms: 4 Cases and Rationale for Systematic Studies
Published: June 24, 2022 | 10.20411/pai.v7i1.518

Elevated Plasma Soluble ST2 Levels are Associated With Neuronal Injury and Neurocognitive Impairment in Children With Cerebral Malaria
Published: June 23, 2022 | 10.20411/pai.v7i1.499

Why Does Doxycycline Pose a Relatively Low Risk for Promotion of Clostridioides difficile Infection?
Published: June 21, 2022 | 10.20411/pai.v7i1.512

Ultraviolet-C Light-emitting Device Against Microorganisms in Beauty Salons
Published: June 16, 2022 | 10.20411/pai.v7i1.497

Erica Ollmann Saphire: How the Study of HIV and Other Viruses Informed the Rapid Development of Vaccines and Therapeutic Antibodies Against COVID-19
Published: May 2, 2022 | 10.20411/pai.v7i1.515

Planes, Trains, and Automobiles: Use of Carbon Dioxide Monitoring to Assess Ventilation During Travel
Published: Feb. 25, 2022 | 10.20411/pai.v7i1.495

SARS in Cars: Carbon Dioxide Levels Provide a Simple Means to Assess Ventilation in Motor Vehicles
Published: Feb. 2, 2022 | 10.20411/pai.v7i1.493

A Pilot Single Cell Analysis of the Zebrafish Embryo Cellular Responses to Uropathogenic Escherichia coli Infection
Published: Feb. 4, 2022 | 10.20411/pai.v7i1.479


Interested in submitting to this journal?

Pathogens and Immunity is an open access journal that publishes original research, reviews and commentaries focused on pathogens, host defenses, and other clinically relevant aspects of immunity. Pathogens and Immunity does not charge fees to authors.

  • Online submissions are rapid (less than 5 minutes).
  • Currently there are no charges to authors for submission or publication.
  • We review submissions in any National Library of Medicine-approved format.
  • Manuscripts only need to be revised to fit the journal format after acceptance.
  • Reviewers receive a modest cash payment for reviews completed in a timely manner.
  • Authors may, if they wish, provide unedited complete reviews from another named journal together with their response to these critiques that may assist in the review.
  • Articles are indexed on PubMed, PubMed Central, Google Scholar and the Directory of Open Access Journals.

We recommend that you review the About the Journal page for the journal's policies, as well as the Author Guidelines.


Previous Issues

View All Issues