B-Cell Responses to Sars-Cov-2 mRNA Vaccines

Main Article Content

Lela Kardava
Clarisa M. Buckner
Susan Moir

Abstract

Most vaccines against viral pathogens protect through the acquisition of immunological memory from long-lived plasma cells that produce antibodies and memory B cells that can rapidly respond upon an encounter with the pathogen or its variants. The COVID-19 pandemic and rapid deployment of effective vaccines have provided an unprecedented opportunity to study the immune response to a new yet rapidly evolving pathogen. Here we review the scientific literature and our efforts to understand antibody and B-cell responses to SARS-CoV-2 vaccines, the effect of SARS-CoV-2 infection on both primary and secondary immune responses, and how repeated exposures may impact outcomes.

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How to Cite
1.
Kardava L, Buckner C, Moir S. B-Cell Responses to Sars-Cov-2 mRNA Vaccines. PAI [Internet]. 2022 Dec. 9 [cited 2023 Feb. 3];7(2):93-119. Available from: https://www.paijournal.com/index.php/paijournal/article/view/550
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Reviews

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